Notes on the meaning, structure and function of Endoplasmic reticulum. Endoplasmic reticulum occurs in all the eucaryotic cells except RBC of mammals. It forms an intercommunicating system of channels between nuclear membrane and cell membrane.
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The difference between Smooth Endoplasmic Reticulum and Rough Endoplasmic Reticulum are in SER is not associated with ribosomes where RER is studded with ribosomes.
The electron microscope reveals an extensive membrane system in the cytoplasm called Endoplasmic reticulum (ER). It was first reported by Porter in 1945. This continuous membrane system joins the nuclear membrane on one end and the cell membrane on the other.
An American cell biologist, Porter (1960-61) described endoplasmic reticulum for the first time. His observation was based on electron microscopy. Endoplasmic reticulum is a network of tube-like structures distributed extensively throughout the cytoplasm.