The power to bring new hopes to a sick child; to be able to free a dialysis patient; to offer another human being the most wonderful gift: organ transplantation, a gift of life. With this perception we have to approach the transplantation of human organs. The transplants have become a standard medical procedure to preserve the life of thousands of hopeless patients throughout the world. Organ transplantation, once an uncommon, often extraordinary event, has rightfully assumed a prominent position among routine procedures performed at most medical centers. Few endeavors in medicine enable the physician to profoundly influence change in a patient’s physiology and thereby improve the quality of life. Rapid expansion of the scientific foundations of immunology and surgery, as they apply to transplantation, has contributed to the accelerated growth in this field.