The acrosome occurs at the anterior side of the sperm nucleus. It is derived from the golgi complex and chemically it consists of protein digesting enzymes. At the time of acrosome formation the golgi complex gets associated with one or two vacuoles. These vacu­oles enlarge in size and develop a dense granule known as proacrosomal granule.

This granule is rich in mucopolysaccharides. Further enlargement of the vacuole makes it come very close to the sperm nucleus. Eventually the proacrosomal granule enlarges and forms the acrosome. At this stage the rest of the materials of the golgi complex gets reduced in size and are discarded from the sperms as “golgi rest”.