There are several types of B cell defects that lead to “hypogammaglobulinemia”. Sever reduction in antibodies is a characteristic feature of hypogammaglobulinemia syndrome.
This immune deficiency is an outcome of both inherited and developmental disorders.
The common defects associated with B-cell function are:
a) X-linked agammagloubulin anemia
b) IgA deficiency
c) IgG sub class deficiency
d) Immuno deficiency with increased IgM
e) Common variable immuno deficiency
f) Transient hypo gammaglobulin anemia of infancy.