Different animals have different arrangements (or organs) for excretion, which depend on the constitution of the animal. For example:

1. In Amoeba (and other single celled animals), the waste material carbon dioxide is removed by diffusion through the cell membrane, but nitrogenous wastes (like ammonia) and excess water are removed by the contractile vacuole.

2. In earthworm, the tubular structures called nephridia are the excretory organs. In addition to nephridia, the moist skin of earthworm also acts as an excretory organ.

3. In human beings, the microscopic thin tubules form nephron, which functions as excretory unit. About 1 million nephrons taken together form the excretory organ of human beings called kidney.

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Removal of Waste Products in Humans :

All the time (even when we are asleep), our body produces waste substances. The major wastes produced f by the human body is: Carbon dioxide and Urea. Carbon dioxide is produced as a waste by the oxidation of food during the process of respiration. Urea is produced as a waste by the decomposition of unused proteins in the liver. Our body must get rid of these waste materials because their accumulation in the body is poisonous and harms us. Waste removal is called excretion.

The human body has different organs for the removal of wastes from the body. These are our lungs and kidneys. Our lungs excrete carbon dioxide. Our kidneys excrete urea. The kidneys are the main excretory organs of the human body. So, the main excretory system in human beings involves the kidneys. We will first describe how lungs excrete carbon dioxide and then study the main excretory system of human body.

The lungs remove respiratory waste carbon dioxide. This happens as follows: Carbon dioxide is produced as a waste product in the body by the oxidation of food during respiration. This carbon dioxide enters from the body tissues into the blood stream by diffusion. Blood carries this carbon dioxide to the lungs. When we breathe out, then the lungs excrete carbon dioxide which goes into the air through nostrils.

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Thus, our lings act as the excretory organs for removing product urea produced by the waste product carbon dioxide from decomposition of unused proteins the body.

Excretion in Humans :

The excretory system of human beings collects the liquid wastes of the body and helps it get rid of them. The excretory system of human beings consists of the following main organs: Two kidneys, Two ureters, Bladder and Urethra. The kidneys are bean shaped organs towards the back of our body just above the waist.

Every person has two kidneys. The blood in our body is constantly passing through our kidneys. The renal artery (or kidney artery) brings in the dirty blood (containing waste substances) into the kidneys. The function of kidneys is to remove the poisonous substance urea, other waste salts and excess water from the blood and excrete them in the form of yellowish liquid called urine.

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Thus, kidneys clean our blood by filtering it to remove unwanted substances present in it. The cleaned blood is carried away from the kidneys by the renal vein (or kidney vein). The ureters (or excretory tubes), one from each kidney, opens into urinary bladder.

Ureters are the tubes which carry urine from the kidneys to the bladder. Urine is stored in the bladder. The bladder is a bag which stores urine till the time we go to the toilet. The urethra is a tube. The urine collected in the bladder is passed out from the body through the urethra. We will now describe a kidney in detail.

It shows a kidney which has been cut open to show the inner structure. Each kidney is made up of a large number of excretory units called nephrons (We have shown only one nephron to make things simple). The Nephron- nephron has a cup-shaped bag at its upper end which is called Bowman’s capsule. The lower end of Bowman’s capsule is tube-shaped and it is called a tubule. The Bowman’s capsule and the tubule taken together make a nephron. One end of the tubule is connected to the Bowman’s capsule and its other end is connected to a urine-collecting duct of the kidney. The Bowman’s capsule contains a bundle of blood capillaries which is called glomerulus (plural glomeruli). One end of the glomerulus is attached to the renal artery which brings the dirty blood containing the urea waste into it. The other end of glomerulus comes out of Bowman’s capsule as a blood capillary, surrounds the! tubule of nephron and finally joins a renal vein (putting urea-free clean blood into it).

The function of glomerulus is to filter the blood passing through it. Only the small molecules of substances present in blood like glucose, amino acids, salts, urea and water, etc., pass through the glomerulus and collect as filtrate in the Bowman’s capsule. The large molecules like proteins and blood cells cannot pass out through the glomerulus capillaries and hence remain behind in the blood.

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The function of tubule off nephron is to allow the selective reabsorption of the useful substances like glucose, amino acids, salts and water into the blood capillaries (which surround it). But the waste material like urea remains behind in the tubule. It does not get reabsorbed into blood capillaries. We will now describe the working of the excretory system of humans.

In order to understand the working of the excretory system of humans, we will use a highly magnified diagram of a nephron. The dirty blood containing waste like urea (brought by renalartery) enters the glomerulus. The glomerulus filters this blood. During filtration, the substances like glucose, amino acids, salts, water and urea, etc., present in the blood pass into Bowman’s capsule and then enter the tubule of nephron. When the filtrate containing useful substances as well as the waste substances passes through the tubule, then the useful substances like all glucose, all amino acids, most salts, and most water, etc., are reabsorbed into the blood through blood capillaries surrounding the tubule. Only the waste substances urea, some unwanted salts and excess water remain behind in the tubule. The liquid left behind in the tubule of nephron is urine.

The nephron carries this urine into the collecting duct of the kidney from where it is carried to ureter. From the ureter, urine passes into urinary bladder. Urine is stored in the bladder for some time and ultimately passed out of the body through urethra. Please note that the human urine contains water, some salts and nitrogenous substances, most of which is urea (and some uric acid).

Renal Failure (Kidney Failure) and the Technology for Survival :

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Sometimes, a person’s kidneys may stop working. An infection in the kidneys, an injury to kidneys, very high blood pressure, very high blood sugar or restricted blood flow to the kidneys, can damage the kidneys due to which they stop working. Complete failure of the kidneys allows the urea and other waste products to build up in the blood. Even the amount of water in the body is not regulated. This will cause death if the patient is not given immediate treatment.

The best long term solution for kidney failure is the kidney transplant. The damaged kidney is removed and a matching kidney donated by a healthy person is transplanted in its place by a surgical operation. If a kidney transplant is not possible due to some reasons, then the patient with kidney failure is treated periodically on a kidney machine (by a procedure called dialysis). This is because a kidney machine can do the work of damaged kidneys. The kidney machine is sometimes called ‘artificial kidney’. An artificial kidney is a device to remove nitrogenous waste products from the blood through dialysis.

Dialysis :

The blood of a person having kidney failure can be cleaned regularly by using a kidney machine (or dialysis machine). The procedure used for cleaning the blood of a person by separating the waste substance (urea) from it is called dialysis. The principle of dialysis is explained below.

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The blood from an artery in the patient’s arm is made to flow into the dialyser of a dialysis machine made of long tubes of selectively permeable membrane (like cellulose) which are coiled in a tank containing dialysing solution. The dialysing solution contains water, glucose and salts in similar concentrations to those in normal blood. As the patient’s blood passes through the dialysing solution, most of the wastes like urea present in it pass through the selectively permeable cellulose tubes into the dialysing solution. The clean blood is pumped back into a vein of the patient’s arm.

Sample Problem:

The kidneys in human beings are a part of the system for:

(a) nutrition (b) respiration

(c) excretion (d) transportation

Answer:

(c) excretion.