Integral proteins serve as:
(i) channels that permit the passage of selected ions through the membrane;
(ii) carriers (or transporters) ‘that ferry substances across the membrane by binding to them;
(iii) pumps that are carriers which can split ATP and use the energy derived for membrane transport of substrates;
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(iv) receptors (located on the outside) which bind to specific molecules and send a chemical signal to the cell interior, initiating intracellular reactions;
(v) enzymes, catalyzing reactions at the membrane surfaces – both outer and inner.